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Healthcare Business Review | Monday, February 10, 2025
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Ketamine is a promising treatment for depression, especially for those who have not found relief through conventional methods.
FREMONT, CA: Ketamine, once used as a recreational drug and anesthetic, is currently being studied for its potential to treat severe depressive disorders. This has sparked interest and discussion among patients seeking alternative antidepressants, as well as within the medical community.
Ketamine’s journey from operating room staple to psychiatric breakthrough is a fascinating one. Initially developed in the 1960s as an anesthetic, ketamine has long been recognized for its fast-acting properties. However, its potential for treating depression was not immediately evident. It wasn't until the early 2000s that scientists started looking into its effects on mood disorders. They found that it might quickly relieve depressive symptoms, primarily when other therapies hadn't worked.
Ketamine's rapid onset of effects is among its most alluring features. Ketamine frequently provides relief in a matter of hours or days, in contrast to conventional antidepressants, which might take weeks or even months to show results. For those with intense suicidal thoughts or severe, treatment-resistant depression, this quick onset is especially helpful. While ketamine acts through a distinct method, targeting the glutamate system, traditional antidepressants work by gradually changing brain chemistry, mainly through the serotonin system. Its quick effect on mood is explained by this innovative method.
Ketamine is typically administered in a clinical setting through intravenous infusion, intranasal spray, or oral formulations. The intravenous route involves a series of infusions over time and has been most extensively studied.